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Article

Genes linked to hearing and vestibular phenotypes in humans and mice: an interspecies systematic review.

Human genomics - 22 Dec 2025

Ayoub Cedra, Paladugu Saihamsini, Nikitenko Nikita, Lopez-Escamez Jose A

Abstract excerpt

Mouse models are relevant to study functionality of genes involved in human hearing and vestibular disorders; however, other pre-clinical models including organoids could be more suitable depending on the gene and its homology across species. While some mouse models replicate human hearing phenotypes, models for vestibular disorders like Meniere Disease (MD) are lacking. We aimed to identify genes associated with...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41430327
DOI: 10.1186/s40246-025-00891-x
PMCID: PMC12751684

Genes

AVP
CLRN1
GRXCR1
MARVELD2
CCDC88C
CIB2
COL9A2
NIN
OTOG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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