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Article

Medea SUMOylation restricts the signaling range of the Dpp morphogen in the Drosophila embryo.

Genes & development - 15 Sept 2008

Miles Wayne O, Jaffray Ellis, Campbell Susan G, Takeda Shugaku, Bayston Laura J, Basu Sanjay P, Li Mingfa, Raftery Laurel A, Ashe Mark P, Hay Ronald T, Ashe Hilary L

Abstract excerpt

Morphogens are secreted signaling molecules that form concentration gradients and control cell fate in developing tissues. During development, it is essential that morphogen range is strictly regulated in order for correct cell type specification to occur. One of the best characterized morphogens is Drosophila Decapentaplegic (Dpp), a BMP signaling molecule that patterns the dorsal ectoderm of the embryo by...

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PMID: 18794353
DOI: 10.1101/gad.494808
PMCID: PMC2546696

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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