Article
Investigation of Frizzled-5 during embryonic neural development in mouse.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jun 2008
Burns Carole J, Zhang Jianmin, Brown Erinn C, Van Bibber Alyssa M, Van Es Johan, Clevers Hans, Ishikawa Tomo-o, Taketo M Mark, Vetter Monica L, Fuhrmann Sabine
Abstract excerpt
Recent studies revealed that the Wnt receptor Frizzled-5 (Fzd5) is required for eye and retina development in zebrafish and Xenopus, however, its role during mammalian eye development is unknown. In the mouse embryo, Fzd5 is prominently expressed in the pituitary, distal optic vesicle, and optic stalk, then later in the progenitor zone of the developing retina. To elucidate the role of Fzd5 during eye...
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