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Article

Transcriptional upregulation of p21/WAF/Cip1 in myeloid leukemic blasts expressing AML1-ETO.

Haematologica - 1 Nov 2008

Berg Tobias, Fliegauf Manfred, Burger Jan, Staege Martin S, Liu Shaohua, Martinez Natalia, Heidenreich Olaf, Burdach Stefan, Haferlach Torsten, Werner Milton H, Lübbert Michael

Abstract excerpt

An inducible model for conditional expression of AML1-ETO in myeloid U-937 cells was generated previously to determine cellular effects of AML1-ETO and to identify target genes. Induction of AML1-ETO expression in U-937 resulted in reduced cell growth, G1 arrest and apoptosis. Microarray analysis...

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Source

Identifiers

PMID: 18790797
DOI: 10.3324/haematol.13044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18790797-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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