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Article

The fold recognition of CP2 transcription factors gives new insights into the function and evolution of tumor suppressor protein p53.

Cell cycle (Georgetown, Tex.) - 15 Sept 2008

Kokoszynska Katarzyna, Ostrowski Jerzy, Rychlewski Leszek, Wyrwicz Lucjan S

Abstract excerpt

The CP2 transcription factor (TFCP2) is a critical regulator of erythroid gene expression. Apart from the involvement in the transcriptional switch of globin gene promoters it activates an array of cellular and viral gene promoters. A number of homologous proteins was identified in genomes of Metazoa, with additional five homologues encoded by the human genome (TFCP2L1, UBP1, GRHL1, GRHL2, GRHL3). Although...

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Source

Identifiers

PMID: 18787404
DOI: 10.4161/cc.7.18.6680

Genes

GRHL1
GRHL2
GRHL3
TFCP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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