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Characterization of p53 Family Homologs in Evolutionary Remote Branches of Holozoa

18 Dec 2019

Abstract excerpt

The p53 family of transcription factors plays key roles in development, genome stability, senescence and tumor development, and p53 is the most important tumor suppressor protein in humans. Although intensively investigated for many years, its initial evolutionary history is not yet fully elucidated. Using bioinformatic and structure prediction methods on current databases containing newly-sequenced genomes and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31861340
DOI: 10.3390/ijms21010006

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