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Article

Computational detection of significant variation in binding affinity across two sets of sequences with application to the analysis of replication origins in yeast.

BMC bioinformatics - 12 Sept 2008

Keich Uri, Gao Hong, Garretson Jeffrey S, Bhaskar Anand, Liachko Ivan, Donato Justin, Tye Bik K

Abstract excerpt

BACKGROUND: In analyzing the stability of DNA replication origins in Saccharomyces cerevisiae we faced the question whether one set of sequences is significantly enriched in the number and/or the quality of the matches of a particular position weight matrix relative to another set. RESULTS: We pr...

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Identifiers

PMID: 18786274
DOI: 10.1186/1471-2105-9-372
PMCID: PMC2566582

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18786274-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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