Article
[Primary evaluation of anti-HEV diagnostic reagent by experimental infection animal model with hepatitis E virus].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 1 Jan 2008
Zhou Cheng, Huang Wei-jin, Wu Xing, Lan Hai-yun, Gu Wen-jie, Huang Guo-yong, Zhang Hua-yuan, Qi Zi-bai, Li He-min
Abstract excerpt
OBJECTIVE: To evaluate anti-HEV diagnostic kits by experimental infecting rhesus monkeys with HEV. METHODS: Eight rhesus monkeys were infected with genotype 1 and 4 HEV separately. The alanine aminotransferase (ALT) level of all monkeys were detected before and after the process of infection. HEV RNA in stool specimens was tested by reverse transcriptase-polymerase chain reaction (RT-PCR) assay. Anti-HEV IgG in...
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