Article
Clinical significance of anti-HEV IgA in diagnosis of acute genotype 4 hepatitis E virus infection negative for anti-HEV IgM.
Digestive diseases and sciences - 1 Nov 2009
Zhang Shujun, Tian Deying, Zhang Zhengang, Xiong Junhui, Yuan Quan, Ge Shengxiang, Zhang Jun, Xia Ningshao
Abstract excerpt
Anti-HEV IgM is a diagnostic for recent or ongoing HEV infection. However, some patients with acute hepatitis E (AHE) negative for anti-HEV IgM in acute period were often observed in clinical practice. In this study, we constructed the anti-HEV IgA indirect ELISA assay to evaluate the significance of anti-HEV IgA. The specificity of anti-HEV IgA was 99.6%. Among 245 AHE patients, 84 samples from 84 patients were...
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