Article
Susceptibility of laboratory rats against genotypes 1, 3, 4, and rat hepatitis E viruses.
Veterinary microbiology - 12 Apr 2013
Li Tian-Cheng, Yoshizaki Sayaka, Ami Yasushi, Suzaki Yuriko, Yasuda Shumpei P, Yoshimatsu Kumiko, Arikawa Jiro, Takeda Naokazu, Wakita Takaji
Abstract excerpt
To determine whether or not rats are susceptible to hepatitis E virus (HEV) infection, each of group containing three laboratory rats (Wistar) were experimentally inoculated with genotypes 1, 3, 4 and rat HEV by intravenous injection. Serum and stool samples were collected and used to detect HEV RNA and anti-HEV antibodies by RT-PCR and ELISA, respectively. The virus infection was monitored up to 3 months after...
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