Article
The voltage-gated Na+ channel Nav1.8 contains an ER-retention/retrieval signal antagonized by the beta3 subunit.
Journal of cell science - 1 Oct 2008
Zhang Zhen-Ning, Li Qian, Liu Chao, Wang Hai-Bo, Wang Qiong, Bao Lan
Abstract excerpt
Voltage-gated Na(+) channel (Na(v)) 1.8 contributes to the majority of the Na(+) current that underlies the depolarizing phase of action potentials. Na(v)1.8 is mainly distributed intracellularly and its current amplitude can be enhanced by the beta3 subunit. However, little is known about the me...
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