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Screening a limited structure-based library identifies UDP-GalNAc-specific mutants of alpha-1,3-galactosyltransferase.

Glycobiology - 1 Dec 2008

Tumbale Percy, Jamaluddin Haryati, Thiyagarajan Nethaji, Acharya K Ravi, Brew Keith

Abstract excerpt

Complex glycans have important roles in biological recognition processes and considerable pharmaceutical potential. The synthesis of novel glycans can be facilitated by engineering glycosyltransferases to modify their substrate specificities. The choice of sites to modify requires the knowledge o...

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PMID: 18782853
DOI: 10.1093/glycob/cwn083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18782853-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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