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Article

Triggering protein folding within the GroEL-GroES complex.

The Journal of biological chemistry - 14 Nov 2008

Madan Damian, Lin Zong, Rye Hays S

Abstract excerpt

The folding of many proteins depends on the assistance of chaperonins like GroEL and GroES and involves the enclosure of substrate proteins inside an internal cavity that is formed when GroES binds to GroEL in the presence of ATP. Precisely how assembly of the GroEL-GroES complex leads to substrate protein encapsulation and folding remains poorly understood. Here we use a chemically modified mutant of GroEL...

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Identifiers

PMID: 18782766
DOI: 10.1074/jbc.M802898200
PMCID: PMC2581556

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Triggering protein folding within the GroEL-GroES complex.PMID 18782766Read ↗

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