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Article

Elucidation of steps in the capture of a protein substrate for efficient encapsulation by GroE.

The Journal of biological chemistry - 28 Jul 2006

Cliff Matthew J, Limpkin Claire, Cameron Angus, Burston Steven G, Clarke Anthony R

Abstract excerpt

We have identified five structural rearrangements in GroEL induced by the ordered binding of ATP and GroES. The first discernable rearrangement (designated T --> R(1)) is a rapid, cooperative transition that appears not to be functionally communicated to the apical domain. In the second (R(1) --> R(2)) step, a state is formed that binds GroES weakly in a rapid, diffusion-limited process. However, a second optical...

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Identifiers

PMID: 16684774
DOI: 10.1074/jbc.M601605200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Elucidation of steps in the capture of a protein substrate for efficient encapsulation by GroE.PMID 16684774Read ↗

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