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Article

Study of the impact of perilipin polymorphisms in a French population.

Journal of negative results in biomedicine - 12 Jul 2006

Meirhaeghe Aline, Thomas Séverine, Ancot Frédéric, Cottel Dominique, Arveiler Dominique, Ferrières Jean, Amouyel Philippe

Abstract excerpt

BACKGROUND: Perilipins are proteins localized at the surface of the lipid droplet in adipocytes, steroid-producing cells and ruptured atherosclerotic plaques playing a role in the regulation of triglyceride deposition and mobilization. We investigated whether perilipin gene polymorphisms were associated with obesity, type 2 diabetes, and their related variables (anthropometric variables, plasma leptin, lipids,...

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Source

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Identifiers

PMID: 16836753
DOI: 10.1186/1477-5751-5-10
PMCID: PMC1538627

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Study of the impact of perilipin polymorphisms in a French population.PMID 16836753Read ↗

Genetic variation at the perilipin (PLIN) locus is associated with obesity-related phenotypes in White women.Semantic proximity Read ↗

Polymorphisms in perilipin gene (PLIN) are not associated with obesity and weight variation in people with high risk of type 2 diabetes.Semantic proximity Read ↗

Association between three genetic variants of the Perilipin Gene (PLIN) and glucose metabolism: results from a replication study among Chinese adults and a meta-analysis.Semantic proximity Read ↗

Gender-specific association of a perilipin gene haplotype with obesity risk in a white population.Semantic proximity Read ↗

Intragenic linkage disequilibrium structure of the human perilipin gene (PLIN) and haplotype association with increased obesity risk in a multiethnic Asian population.Semantic proximity Read ↗

Perilipin polymorphisms are risk factors for the development of obesity in adolescents? A case-control study.Semantic proximity Read ↗

Common variations in perilipin gene, central obesity, and risk of type 2 diabetes in US women.Semantic proximity Read ↗

Effects of perilipin (PLIN) gene variation on metabolic syndrome risk and weight loss in obese children and adolescents.Semantic proximity Read ↗

Genetic variation at the perilipin locus is associated with changes in serum free fatty acids and abdominal fat following mild weight loss.Semantic proximity Read ↗

Variation in the perilipin gene (PLIN) affects glucose and lipid metabolism in non-Hispanic white women with and without polycystic ovary syndrome.Semantic proximity Read ↗

A functional variant in the exon 5 of PLIN1 reduces risk of central obesity by possible regulation of lipid storage.Semantic proximity Read ↗

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