Article
Association between Val/Leu(247) polymorphism of apolipoprotein H and cerebral infarction in a Chinese population.
Journal of thrombosis and thrombolysis - 1 Aug 2009
Xia Jian, Yuan Mei, Xu Hong-wei, Zhang Le, Du Xiao-ping, Liu Yun-hai, Yang Qi-dong
Abstract excerpt
BACKGROUND: Antiphospholipid antibodies (aPL) are considered to be a cause of an acquired hypercoagulable state leading to cerebral infarction (CI). Apolipoprtein H (apoH) is an important target antigen for aPL and thus apoH polymorphisms may influence aPL production and the development of CI. The purpose of this study was to identify associations between the Val/Leu(247) polymorphism of apoH gene and CI in a...
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