Article
Apolipoprotein H (apoH)-dependent autoantibodies and apoH protein polymorphism in selected patients showing lupus anticoagulant activity.
Clinical chemistry and laboratory medicine - 1 Jan 2005
Vogrinc Zeljka, Trbojević-Cepe Milica, Coen Désirée, Vitale Ksenija, Stavljenić-Rukavina Ana
Abstract excerpt
Apolipoprotein H (apoH) is considered to be a necessary cofactor for the binding of certain antiphospholipid antibodies to anionic phospholipids. Some apoH-dependent antiphospholipid antibodies also exert lupus anticoagulant (LA) activity, which seems to depend on antiphospholipid antibody epitope specificity. The aim of this study was to evaluate whether the presence of less frequent apoH alleles may induce...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
