Article
Variation of the factor VII gene and ischemic heart disease in Japanese subjects.
Coronary artery disease - 1 Dec 1999
Tamaki S, Iwai N, Nakamura Y, Tsujita Y, Kinoshita M
Abstract excerpt
BACKGROUND: Polymorphisms of the 5' region (5'FT), an intronic mutation (IVS7), and the 353Arg-Gln (R353Q) substitution of the factor VII gene have been reported to be associated with the plasma level of factor VII. Greater than normal levels of factor VII have also been reported to be associated with atherothrombotic events. However, the significance of factor VII gene polymorphism in the pathogenesis of...
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