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Article

Sensitive DNA probe for photochemical ligation prepared in click chemistry.

Nucleic acids symposium series (2004) - 1 Jan 2008

Ami Takehiro, Matsumura Hiroshi, Fujimoto Kenzo

Abstract excerpt

We report a new photosensitive probe, that takes advantage of the electronic structural changes associated with the triazole ring formed in the Cu(I)-catalyzed Huisgen 1,3-dipolar cycloaddition. We succeeded in performing photoligation on the second time scale. Huisgen cycloaddition are employed to various labeling. As an example, we report a procedure for preparing the DNA probe for quick SNP typing.

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Identifiers

PMID: 18776346
DOI: 10.1093/nass/nrn125

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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