Article
Tumor necrosis factor alpha-308 gene polymorphism in patients with anorexia nervosa.
The Turkish journal of pediatrics - 1 Jan 2000
Kanbur Nuray, Mesci Lütfiye, Derman Orhan, Turul Tuğba, Cuhadaroğlu Füsun, Kutluk Tezer, Tezcan Ilhan
Abstract excerpt
Tumor necrosis factor alpha (TNF-alpha) is a principal cytokine that may induce weight loss. TNF-alpha -308 G to A polymorphism increases transcription of TNF-alpha in vitro. The aim of this study was to investigate whether TNF-alpha gene promoter polymorphism at position -308 (G to A substitution) is one of the factors playing a role in the development of anorexia nervosa (AN). Sixteen patients with AN, aged...
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