Assessment of telomere length, phenotype, and DNA content.

doi:10.1002/0471142956.cy0726s29

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Article

Assessment of telomere length, phenotype, and DNA content.

Current protocols in cytometry - 1 Sept 2004

Schmid Ingrid, Jamieson Beth D

Abstract excerpt

Telomere sequences at the end of chromosomes control somatic cell division; therefore, telomere length in a given cell population provides information about its replication potential. This unit describes a method for flow cytometric measurement of telomere length in subpopulations using fluorescence in situ hybridization of fluorescently-labeled probes (Flow-FISH) without prior cell separation. After cells are...

Topics

Animals
DNA
Flow Cytometry
Humans
In Situ Hybridization, Fluorescence
Phenotype
Ploidies
Resting Phase, Cell Cycle
Telomere

Source

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Identifiers

PMID: 18770803
DOI: 10.1002/0471142956.cy0726s29
PMCID: PMC5053762

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