Article
Assessing telomeric phenotypes.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2006
LeBel Catherine, Larrivée Michel, Bah Amadou, Laterreur Nancy, Lvesque Nancy, Wellinger Raymund J
Abstract excerpt
The concept of telomeres as being the end-part of eukaryotic chromosomes was first described by H. J. Muller and B. McClintock. Their pioneering work opened the path for multiple new researches and assays on a thrilling subject, with implications for various domains such as aging, replication, immortality, and cancer. Yeast has been a model of choice to study telomere length, senescence, telomerase activity,...
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