Article
The frequency of the H402 allele of CFH and its involvement with age-related maculopathy in an aged Black African Xhosa population.
Ophthalmic genetics - 1 Sept 2008
Ziskind Ari, Bardien Soraya, van der Merwe Lize, Webster Andrew R
Abstract excerpt
The H402 allele of the CFH gene is an established risk factor for age-related maculopathy (ARMD) in Caucasians, accounting for approximately 60% of the genetic risk at the population level. In general, the advanced forms of ARMD are rare in Black populations in Africa, as well as Black populations who have lived for generations in the United States or the West Indies, although there are reports that the earlier...
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