Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deletion of BBA64, BBA65, and BBA66 loci does not alter the infectivity of Borrelia burgdorferi in the murine model of Lyme disease.

Infection and immunity - 1 Nov 2008

Maruskova Mahulena, Seshu J

Abstract excerpt

Borrelia burgdorferi, the causative agent of Lyme disease, alters its gene expression in response to highly disparate environmental signals encountered in its tick vector versus vertebrate hosts. Whole-genome transcriptional profile analysis of B. burgdorferi, propagated in vitro under mammalian-host-specific conditions, revealed significant upregulation of several linear plasmid 54 (lp54)-encoded open reading...

Topics

Join the communities discussing this publication.

Antigens, Bacterial
Blotting, Southern
Blotting, Western
Borrelia burgdorferi
Electrophoresis, Polyacrylamide Gel

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Expression

Mice, Inbred C3H

Source

Open in PubMed Open full text

Identifiers

PMID: 18765733
DOI: 10.1128/IAI.00803-08
PMCID: PMC2573326

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deletion of BBA64, BBA65, and BBA66 loci does not alter the infectivity of Borrelia burgdorferi in the murine model of Lyme disease.PMID 18765733Read ↗

Role of the BBA64 locus of Borrelia burgdorferi in early stages of infectivity in a murine model of Lyme disease.Semantic proximity Read ↗

Competitive advantage of Borrelia burgdorferi with outer surface protein BBA03 during tick-mediated infection of the mammalian host.Semantic proximity Read ↗

In Vivo Expression Technology Identifies a Novel Virulence Factor Critical for Borrelia burgdorferi Persistence in MiceSemantic proximity Read ↗

A Differential Role for BB0365 in the Persistence ofBorrelia burgdorferiin Mice and TicksSemantic proximity Read ↗

Functional analysis of the Borrelia burgdorferi bba64 gene product in murine infection via tick infestation.Semantic proximity Read ↗

<i>Borrelia burgdorferi</i>Gene Expression In Vivo and Spirochete PathogenicitySemantic proximity Read ↗

The bba64 gene of Borrelia burgdorferi, the Lyme disease agent, is critical for mammalian infection via tick bite transmission.Semantic proximity Read ↗

Borrelia burgdorferi bba74Is Expressed Exclusively during Tick Feeding and Is Regulated by Both Arthropod- and Mammalian Host-Specific SignalsSemantic proximity Read ↗

bptA ( bbe16 ) is essential for the persistence of the Lyme disease spirochete, Borrelia burgdorferi , in its natural tick vectorSemantic proximity Read ↗

Temporal Expression Analysis of the Borrelia burgdorferi Paralogous Gene Family 54 Genes BBA64, BBA65, and BBA66 during Persistent Infection in MiceSemantic proximity Read ↗

Decreased infectivity in Borrelia burgdorferi strain B31 is associated with loss of linear plasmid 25 or 28-1.Semantic proximity Read ↗

BBE02 disruption mutants of Borrelia burgdorferi B31 have a highly transformable, infectious phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.