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Article

BBE02 disruption mutants of Borrelia burgdorferi B31 have a highly transformable, infectious phenotype.

Infection and immunity - 1 Dec 2004

Kawabata Hiroki, Norris Steven J, Watanabe Haruo

Abstract excerpt

We constructed highly transformable and infectious Borrelia burgdorferi B31 by inactivating BBE02, a putative restriction-modification gene on the linear plasmid lp25. The low-passage-number B31 clones 5A4 (containing all plasmids) and 5A18 (lp28-4(-) lp56(-)) were used for this study, and BBE02 was disrupted by homologous recombination. The transformation efficiency with the shuttle vector pBSV2C03::gntDeltakan...

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Identifiers

PMID: 15557639
DOI: 10.1128/IAI.72.12.7147-7154.2004
PMCID: PMC529111

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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