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Article

Functional analysis of the Borrelia burgdorferi bba64 gene product in murine infection via tick infestation.

PloS one - 3 May 2011

Patton Toni G, Dietrich Gabrielle, Dolan Marc C, Piesman Joseph, Carroll James A, Gilmore Robert D

Abstract excerpt

Borrelia burgdorferi, the causative agent of Lyme borreliosis, is transmitted to humans from the bite of Ixodes spp. ticks. During the borrelial tick-to-mammal life cycle, B. burgdorferi must adapt to many environmental changes by regulating several genes, including bba64. Our laboratory recently demonstrated that the bba64 gene product is necessary for mouse infectivity when B. burgdorferi is transmitted by an...

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Antigens, Bacterial
Borrelia burgdorferi
Ixodes
Lyme Disease
Microscopy, Fluorescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Myeloid Differentiation Factor 88

Tick Infestations

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PMID: 21559293
DOI: 10.1371/journal.pone.0019536
PMCID: PMC3086921

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Functional analysis of the Borrelia burgdorferi bba64 gene product in murine infection via tick infestation.PMID 21559293Read ↗

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