Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Differential Role for BB0365 in the Persistence ofBorrelia burgdorferiin Mice and Ticks

18 Dec 2007

Abstract excerpt

Borrelia burgdorferi, the etiologic agent of Lyme disease, persists in both an arthropod vector and vertebrate hosts, usually wild rodents. Analysis of the B. burgdorferi transcriptome in vivo indicates that the bb0365 gene is markedly induced as spirochetes enter the feeding ticks from infected mice. To understand the importance of the bb0365 gene product in the spirochete life cycle, we inactivated this gene in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dermatological diseases and infestations
Share to Vector-borne infectious diseases
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18171298
DOI: 10.1086/523764

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Differential Role for BB0365 in the Persistence ofBorrelia burgdorferiin Mice and TicksPMID 18171298Read ↗

Borrelia burgdorferi bba66 Gene Inactivation Results in Attenuated Mouse Infection by Tick TransmissionSemantic proximity Read ↗

Functional analysis of the Borrelia burgdorferi bba64 gene product in murine infection via tick infestation.Semantic proximity Read ↗

The bba64 gene of Borrelia burgdorferi, the Lyme disease agent, is critical for mammalian infection via tick bite transmission.Semantic proximity Read ↗

BB0323 function is essential for Borrelia burgdorferi virulence and persistence through tick-rodent transmission cycle.Semantic proximity Read ↗

Deletion of BBA64, BBA65, and BBA66 loci does not alter the infectivity of Borrelia burgdorferi in the murine model of Lyme disease.Semantic proximity Read ↗

Characterization of the highly regulated antigen BBA05 in the enzootic cycle of Borrelia burgdorferi.Semantic proximity Read ↗

Role of the BBA64 locus of Borrelia burgdorferi in early stages of infectivity in a murine model of Lyme disease.Semantic proximity Read ↗

Temporal Expression Analysis of the Borrelia burgdorferi Paralogous Gene Family 54 Genes BBA64, BBA65, and BBA66 during Persistent Infection in MiceSemantic proximity Read ↗

Population Bottlenecks during the Infectious Cycle of the Lyme Disease Spirochete Borrelia burgdorferiSemantic proximity Read ↗

BBA52 facilitates Borrelia burgdorferi transmission from feeding ticks to murine hosts.Semantic proximity Read ↗

In Vivo Expression Technology Identifies a Novel Virulence Factor Critical for Borrelia burgdorferi Persistence in MiceSemantic proximity Read ↗

Competitive advantage of Borrelia burgdorferi with outer surface protein BBA03 during tick-mediated infection of the mammalian host.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.