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Article

Genetic and epigenetic defects in mental retardation.

The international journal of biochemistry & cell biology - 1 Jan 2009

Kramer Jamie M, van Bokhoven Hans

Abstract excerpt

Mental retardation (MR) is a highly diverse group of cognitive disorders. The high incidence of MR, 2-3% in most populations, and the high burden for families and society makes this condition one of the major unsolved problems in modern medicine. Gene defects account for about half of all patient...

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Topics

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Share to Intellectual Disability
Share to Chromatin Assembly and Disassembly
Share to Cognition

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Histone-Lysine N-Methyltransferase

Share to Histone Methyltransferases

Share to Methyl-CpG-Binding Protein 2

Share to Protein Methyltransferases

Source

Identifiers

PMID: 18765296
DOI: 10.1016/j.biocel.2008.08.009

Genes

EHMT1
MECP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18765296-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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