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Article

Disruption of the epigenetic code: an emerging mechanism in mental retardation.

Neurobiology of disease - 1 Jul 2010

van Bokhoven Hans, Kramer Jamie M

Abstract excerpt

Mental retardation (MR) is a highly diverse group of cognitive disorders. Gene defects account for about half of all patients and mutations causative for impaired cognition have been identified in more than 400 genes. While there are numerous genetic defects underlying MR, a more limited number of pathways is emerging whose disruption appears to be shared by groups of MR genes. One of these common pathways is...

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Source

Identifiers

PMID: 20304068
DOI: 10.1016/j.nbd.2010.03.010

Genes

MECP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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