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Article

Epigenetic impacts on neurodevelopment: pathophysiological mechanisms and genetic modes of action.

Pediatric research - 1 May 2011

Zahir Farah R, Brown Carolyn J

Abstract excerpt

Disruptions of genes that are involved in epigenetic functions are known to be causative for several mental retardation/intellectual disability (MR/ID) syndromes. Recent work has highlighted genes with epigenetic functions as being implicated in autism spectrum disorders (ASDs) and schizophrenia (SCZ). The gene-environment interaction is an important factor of pathogenicity for these complex disorders. Epigenetic...

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PMID: 21293311
DOI: 10.1203/PDR.0b013e318213565e

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