Article
Killer immunoglobulin-like receptor gene repertoire influences viral load of primary human cytomegalovirus infection in renal transplant patients.
Genes and immunity - 1 Dec 2014
Jones D C, Peacock S, Hughes D, Traherne J A, Allen R L, Barnardo M C N M, Friend P, Taylor C J, Fuggle S, Trowsdale J, Young N T
Abstract excerpt
Killer cell immunoglobulin-like receptors (KIR) are highly polymorphic members of the immunoglobulin superfamily, which influence the response of natural killer cells and some T-lymphocyte subsets. Analysis of a cohort of previously human cytomegalovirus (HCMV)-negative patients, who developed primary HCMV infection following HCMV-positive renal transplant (n=76), revealed an increase in the frequency of KIR...
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