Article
The effect of single and combined activating killer immunoglobulin-like receptor genotypes on cytomegalovirus infection and immunity after hematopoietic cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation - 1 Mar 2009
Zaia John A, Sun Joel Y, Gallez-Hawkins Ghislaine M, Thao Lia, Oki Arisa, Lacey Simon F, Dagis Andrew, Palmer Joycelynne, Diamond Don J, Forman Stephen J, Senitzer David
Abstract excerpt
It has been shown that activating killer Ig-like receptor (aKIR) genes are important for control of cytomegalovirus (CMV) reactivation after hematopoietic cell transplantation (HCT). To date, using the broad classification of KIR haplotypes A and B, the precise role of individual KIR genes in the control of infection cannot be discerned. To address this, a consecutive case series of 211 non-T cell-depleted HCT...
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