Article
Evidence for an influence of TCF7L2 polymorphism rs7903146 on insulin resistance and sensitivity indices in overweight children and adolescents during a lifestyle intervention.
International journal of obesity (2005) - 1 Oct 2008
Reinehr T, Friedel S, Mueller T D, Toschke A M, Hebebrand J, Hinney A
Abstract excerpt
OBJECTIVE: The T allele of the single-nucleotide polymorphism rs7903146 in TCF7L2 (transcription factor 7 like 2 gene) is associated with type 2 diabetes mellitus. The aim of this study was to analyze whether there is an allele-dosage effect on changes of insulin resistance and sensitivity indice...
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