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Article

The glucocorticoid receptor controls hepatic dyslipidemia through Hes1.

Cell metabolism - 1 Sept 2008

Lemke Ulrike, Krones-Herzig Anja, Berriel Diaz Mauricio, Narvekar Prachiti, Ziegler Anja, Vegiopoulos Alexandros, Cato Andrew C B, Bohl Sebastian, Klingmüller Ursula, Screaton Robert A, Müller-Decker Karin, Kersten Sander, Herzig Stephan

Abstract excerpt

Aberrant accumulation of lipids in the liver ("fatty liver" or hepatic steatosis) represents a hallmark of the metabolic syndrome and is tightly associated with obesity, type II diabetes, starvation, or glucocorticoid (GC) therapy. While fatty liver has been connected with numerous abnormalities of liver function, the molecular mechanisms of fatty liver development remain largely enigmatic. Here we show that...

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Identifiers

PMID: 18762022
DOI: 10.1016/j.cmet.2008.08.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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