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Region between the Canine Distemper Virus M and F Genes Modulates Virulence by Controlling Fusion Protein Expression

28 Aug 2008

Abstract excerpt

Morbilliviruses, including measles and canine distemper virus (CDV), are nonsegmented, negative-stranded RNA viruses that cause severe diseases in humans and animals. The transcriptional units in their genomes are separated by untranslated regions (UTRs), which contain essential transcription and translation signals. Due to its increased length, the region between the matrix (M) protein and fusion (F) protein...

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PMID: 18753197
DOI: 10.1128/jvi.01419-08

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