Article
Na(+)-dependent, active nucleoside transport in S49 mouse lymphoma cells and loss in AE-1 mutant deficient in facilitated nucleoside transport.
Journal of cellular biochemistry - 1 May 1991
Plagemann P G
Abstract excerpt
S49 murine lymphoma cells were examined for expression of various nucleoside transport systems using a non-metabolized nucleoside, formycin B, as substrate. Nitrobenzylthioinosine (NBTI)-sensitive, facilitated transport was the primary nucleoside transport system of the cells. The cells also expressed very low levels of NBTI-resistant, facilitated nucleoside transport as well as of Na(+)-dependent, concentrative...
Topics
- Aminoisobutyric Acids
- Animals
- Biological Transport, Active
- Carrier Proteins
- Dipyridamole
- Formycins
- Kinetics
- Lymphoma
- Membrane Proteins
- Mice
- Mutation