Article
Suppression of GLTSCR2 expression in renal cell carcinomas.
Pathology, research and practice - 1 Feb 2016
Cho Young-Eun, Lee Hyung-Lae, Lim Sung-Jig, Kim Youn-Wha, Choe Bong Keun, Lee Sun, Park Jae-Hoon
Abstract excerpt
Nucleolar protein PICT-1/GLTSCR2 (GLTSCR2) has both tumor suppressive and oncogenic activities, depending on the types of cancer tissue and its expression level. The role of GLTSCR2 in renal cell carcinoma (RCC) has not yet been addressed. The aims of this study were to evaluate GLTSCR2 expression in RCC tissue and to determine pathological significance of GLTSCR2 in terms of tumor grade. RCC and adjacent normal...
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