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Article

Platelet adhesion: a game of catch and release.

The Journal of clinical investigation - 1 Sept 2008

Andrews Robert K, Berndt Michael C

Abstract excerpt

The interaction of circulating platelets with the vessel wall involves a process of cell catch and release, regulating cell rolling, skipping, or firm adhesion and leading to thrombus formation in flowing blood. In this regard, the interaction of platelet glycoprotein Ibalpha (GPIbalpha) with its...

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Share to Blood Platelets
Share to Cell Adhesion
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Platelet Glycoprotein GPIb-IX Complex

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Share to Stress, Mechanical

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Share to von Willebrand Factor

Source

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Identifiers

PMID: 18725992
DOI: 10.1172/JCI36883
PMCID: PMC2518077

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18725992-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Platelet adhesion: a game of catch and release.PMID 18725992Read ↗

Platelet glycoprotein Ibalpha forms catch bonds with human WT vWF but not with type 2B von Willebrand disease vWF.Semantic proximity Read ↗

Selectin-like kinetics and biomechanics promote rapid platelet adhesion in flow: the GPIb(alpha)-vWF tether bond.Semantic proximity Read ↗

Crystal structure of the wild-type von Willebrand factor A1-glycoprotein Ibalpha complex reveals conformation differences with a complex bearing von Willebrand disease mutations.Semantic proximity Read ↗

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Kinetics of GPIbalpha-vWF-A1 tether bond under flow: effect of GPIbalpha mutations on the association and dissociation rates.Semantic proximity Read ↗

New concepts in von Willebrand disease.Semantic proximity Read ↗

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