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Article

A crucial role for hnRNP K in axon development inXenopus laevis

25 Aug 2008

Abstract excerpt

We report that hnRNP K, an RNA-binding protein implicated in multiple aspects of post-transcriptional gene control, is essential for axon outgrowth in Xenopus. Its intracellular localization was found to be consistent with one of its known roles as an mRNA shuttling protein. In early embryos, it was primarily nuclear, whereas later it occupied both the nucleus and cytoplasm to varying degrees in different...

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PMID: 18725517
DOI: 10.1242/dev.022236

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