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Article

High-resolution melting curve analysis for genotyping of common SNP in MTHFR gene using fixed-cell suspension.

Molecular and cellular probes - 1 Jan 2000

Sinthuwiwat Thivaratana, Poowasanpetch Phanasit, Wongngamrungroj Angsana, Promso Somying, Auewarakul Chirayu, Mooney Sean, Tocharoentanaphol Chintana

Abstract excerpt

Genetic variation in MTHFR might explain the interindividual differences in both therapeutic and toxic responses to the treatment of cancer and rheumatoid arthritis with methotrexate, and can be involved in the sensitivity of developing diseases like cancer and congenital anomalies. We investigated the common sequence variation, C677T, in the MTHFR gene in fixed-cell specimens archived after chromosomal analysis...

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Share to MTHFR gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Nucleic Acid Denaturation

Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 18725286
DOI: 10.1016/j.mcp.2008.07.004

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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High-resolution melting curve analysis for genotyping of common SNP in MTHFR gene using fixed-cell suspension.PMID 18725286Read ↗

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