Article
Regulatory networks define phenotypic classes of human stem cell lines.
Nature - 18 Sept 2008
Müller Franz-Josef, Laurent Louise C, Kostka Dennis, Ulitsky Igor, Williams Roy, Lu Christina, Park In-Hyun, Rao Mahendra S, Shamir Ron, Schwartz Philip H, Schmidt Nils O, Loring Jeanne F
Abstract excerpt
Stem cells are defined as self-renewing cell populations that can differentiate into multiple distinct cell types. However, hundreds of different human cell lines from embryonic, fetal and adult sources have been called stem cells, even though they range from pluripotent cells-typified by embryonic stem cells, which are capable of virtually unlimited proliferation and differentiation-to adult stem cell lines,...
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