Article
Positive association of HLA-DRB1*15 with Dupuytren's disease in Caucasians.
Tissue antigens - 1 Aug 2008
Brown J J, Ollier W, Thomson W, Bayat A
Abstract excerpt
Dupuytren's disease (DD) is a permanent nodular condition affecting the palms and digits of the hands, leading to progressive shortening and contractures of the digits often resulting in diminished function and severe deformity. DD is thought to be one of the most common hereditary connective tissue disorders in Caucasians. To elucidate further the aetiology of DD, we compared the HLA-DRB1 phenotype frequencies...
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