HLA-DRB1 polymorphisms distribution in chronic dysimmune polyneuropathy.

doi:10.1016/j.nmd.2008.07.008

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Article

HLA-DRB1 polymorphisms distribution in chronic dysimmune polyneuropathy.

Neuromuscular disorders : NMD - 1 Dec 2008

Gironi M, Guerini F R, Beghi E, Antonini G, Martinelli-Boneschi F, Ceresa L, Morino S, Agliardi C, Ferrante P, Nemni R

Abstract excerpt

The frequency of HLA-DRB1*15 polymorphism, which is strongly associated to multiple sclerosis, was investigated in 84 adult patients with chronic dysimmune polyneuropathy and 272 healthy controls. No significant differences were detected between cases and controls and, among patients, according to gender, peripheral nerve antigen antibody seropositivity, and electrophysiological features. A trend towards an...

Topics

Aged
Chronic Disease
Enzyme-Linked Immunosorbent Assay
Female
Gene Frequency
Genetic Predisposition to Disease
HLA-DR Antigens
HLA-DRB1 Chains
Humans
Male
Middle Aged
Polymerase Chain Reaction
Polymorphism, Genetic
Polyneuropathies

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PMID: 18789688
DOI: 10.1016/j.nmd.2008.07.008

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