Article
A case-control study of the HER2 Ile655Val polymorphism and risk of breast cancer in Taiwan.
Clinical biochemistry - 1 Feb 2008
Lee Su-Chen, Hou Ming-Feng, Hsieh Pei-Chen, Wu Szu-Hsien, Hou Linda Ann, Ma Hsu, Tsai Shin-Meng, Tsai Li-Yu
Abstract excerpt
OBJECTIVES: To investigate the HER2 Ile655Val polymorphism in relation to risk of breast cancer in a case-control study in Taiwan. DESIGN AND METHODS: The HER2 polymorphism at codon 655 was analyzed in 424 patients with breast cancer and 318 controls by using the polymerase chain reaction methodology, followed by the restriction fragment-length polymorphism (PCR-RFLP) analysis. RESULTS: There was a 1.48-fold (95%...
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