Article
C. elegans and H. sapiens mRNAs with edited 3' UTRs are present on polysomes.
RNA (New York, N.Y.) - 1 Oct 2008
Hundley Heather A, Krauchuk Ammie A, Bass Brenda L
Abstract excerpt
Adenosine deaminases that act on RNA (ADARs) are editing enzymes that convert adenosine to inosine in double-stranded RNA (dsRNA). ADARs sometimes target codons so that a single mRNA yields multiple protein isoforms. However, ADARs most often target noncoding regions of mRNAs, such as untranslated regions (UTRs). To understand the function of extensive double-stranded 3' UTR structures, and the inosines within...
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