Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel computational and structural analysis of nsSNPs in CFTR gene

1 Jan 2008

Abstract excerpt

Single Nucleotide Polymorphisms (SNPs) are being intensively studied to understand the biological basis of complex traits and diseases. The Genetics of human phenotype variation could be understood by knowing the functions of SNPs. In this study using computational methods, we analyzed the genetic variations that can alter the expression and function of the CFTR gene responsible candidate for causing cystic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cystic Fibrosis Research Advances
Share to Digestive system and related health
Share to Genomics and Rare Diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18716917
DOI: 10.1007/s11568-008-9019-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel computational and structural analysis of nsSNPs in CFTR genePMID 18716917Read ↗

Analyzing fourteen deleterious nsSNPs of CFTR as promising genetic markers for cancer prognosis.Semantic proximity Read ↗

Applications of computational algorithm tools to identify functional SNPs.Semantic proximity Read ↗

Novel, rare and common pathogenic variants in the CFTR gene screened by high-throughput sequencing technology and predicted by in silico toolsSemantic proximity Read ↗

The CYSMA web server: An example of integrative tool for in silico analysis of missense variants identified in Mendelian disorders.Semantic proximity Read ↗

Genomic, transcriptomic, and protein landscape profile of CFTR and cystic fibrosis.Semantic proximity Read ↗

In Silico Tools and Approaches for the Prediction of Functional and Structural Effects of Single-Nucleotide Polymorphisms on Proteins: An Expert Review.Semantic proximity Read ↗

Computational analysis of functional single nucleotide polymorphisms associated with SLC26A4 gene.Semantic proximity Read ↗

Computational prediction of the effects of non-synonymous single nucleotide polymorphisms in human DNA repair genes.Semantic proximity Read ↗

Prediction of deleterious non-synonymous SNPs based on protein interaction network and hybrid properties.Semantic proximity Read ↗

Genetic analysis and functional study of novel CFTR variants in Chinese children with cystic fibrosis.Semantic proximity Read ↗

Novel frameshift variant of the CFTR gene: S511Lfs*2 from phenotype to molecular predictions.Semantic proximity Read ↗

Computational analysis for the determination of deleterious nsSNPs in human MTHFD1 gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.