Article
Tilting at quixotic trait loci (QTL): an evolutionary perspective on genetic causation.
Genetics - 1 Aug 2008
Weiss Kenneth M
Abstract excerpt
Recent years have seen great advances in generating and analyzing data to identify the genetic architecture of biological traits. Human disease has understandably received intense research focus, and the genes responsible for most Mendelian diseases have successfully been identified. However, the same advances have shown a consistent if less satisfying pattern, in which complex traits are affected by variation in...
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