Article
The genotype-phenotype distinction: from Mendelian genetics to 21st century biology.
Genetica - 1 Aug 2022
Pontarotti Gaëlle, Mossio Matteo, Pocheville Arnaud
Abstract excerpt
The Genotype-Phenotype (G-P) distinction was proposed in the context of Mendelian genetics, in the wake of late nineteenth century studies about heredity. In this paper, we provide a conceptual analysis that highlights that the G-P distinction was grounded on three pillars: observability, transmissibility, and causality. Originally, the genotype is the non-observable and transmissible cause of its observable and...
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