Article
Molecular characteristics in papillary thyroid cancers (PTCs) with no 131I uptake.
Clinical endocrinology - 1 Jan 2008
Mian Caterina, Barollo Susi, Pennelli Gianmaria, Pavan Nicodemo, Rugge Massimo, Pelizzo Maria Rosa, Mazzarotto Renzo, Casara Dario, Nacamulli Davide, Mantero Franco, Opocher Giuseppe, Busnardo Benedetto, Girelli Maria Elisa
Abstract excerpt
OBJECTIVE: Papillary thyroid cancers (PTCs) with no iodine uptake have an aggressive behaviour and a poor prognosis. The aim of our study was to characterize, at molecular level, a subset of PTC with no 131 iodine ((131)I) uptake. DESIGN AND METHODS: Forty-eight cancer tissues were divided into three groups: Group 1, 28 primary cancers; Group 2, 7 recurrences capable of trapping (131)I; and Group 3, 13...
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