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Article

NAT2 fast acetylator genotypes are associated with an increased risk for lung cancer with wildtype epidermal growth factor receptors in Taiwan.

Lung cancer (Amsterdam, Netherlands) - 1 Apr 2009

Lee Chun-Nin, Yu Ming-Chih, Bai Kuan-Jen, Chang Jer-Hua, Fang Chia-Lang, Hsu Han-Lin, Huang Biing-Shiung, Lu Pei-Chih, Liu H Eugene

Abstract excerpt

Identifying the risk factors responsible for lung cancer especially for nonsmokers is critical for both its prevention and treatment. Studies have linked the polymorphisms in N-acetyltransferases (NAT2), a key enzyme for metabolism of hydrocarbons, with lung cancer in Asian female nonsmokers. Since a high percentage of lung adenocarcinoma in Asian female nonsmokers contains activating hotspot mutations in...

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Source

Identifiers

PMID: 18706736
DOI: 10.1016/j.lungcan.2008.07.001

Genes

EGFR
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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